PHD-IN-2 - CAS 2924182-42-1

PHD-IN-2 (Compound 91), a potent PHD antagonist with an IC50 of less than 5 nM, effectively stimulates erythropoietin synthesis in HEP3B cells with an EC50 of less than 2.5 μM. It is applicable for research purposes across various medical fields, including cardiovascular, metabolic, hematological, pulmonary, kidney, liver, and wound healing disorders, as well as cancer [1].

HIF/HIF Prolyl-Hydroxylase

Chromatin/Epigenetic, Metabolism

2924139

C26H27N7O4

501.54

C(OC(C)(C)C)(=O)N1CC2(CN(C2)C3=NC4=C(C=C3)C(O)=C(C(NCC=5C=CC(C#N)=NC5)=O)N=C4)C1

-20°C

Ice Packs

Small Compound