PHD2/HDACs-IN-1 - CAS 2339867-53-5

PHD2/HDACs-IN-1 is a potent mixed inhibitor of PHD2/HDACs, acting on PHD2 (IC50: 1.15 μM), HDAC1 (IC50: 19.75 μM), HDAC2 (IC50: 26.60 μM), and HDAC16 (IC50: 15.98 μM) . HDACs-IN-1 is a low toxicity nephroprotective agent suitable for studies of cisplatin-induced acute kidney injury (AKI) .

Others, HIF/HIF Prolyl-Hydroxylase, HDAC

Metabolism, Others, DNA Damage/DNA Repair, Chromatin/Epigenetic

2339809

C18H19N9O4

425.4

O=C1NC(=NC=C1C(NC2CCN(CC2)C=3N=CC(C(NO)=O)=CN3)=O)N4C=CC=N4

-20°C

Ice Packs

Small Compound