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Molfinity

Phenoxodiol - CAS 81267-65-4

Phenoxodiol - CAS 81267-65-4

MF-0018940-01

$54.85 USD
$54.85 USD
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Product Details

  • Bioactivity

    Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis (XIAP), disrupts FLICE inhibitory protein (FLIP) expression, and sensitizes the cancer cells to Fas-mediated apoptosis. Phenoxodiol induces cell cycle arrest in the G1/S phase of the cell cycle and upregulates p21WAF1 via a p53 independent manner. Phenoxodiol also inhibits DNA topoisomerase II.

  • Target

    Apoptosis, Caspase, p53, Topoisomerase, IAP

  • Related Pathways

    Proteases/Proteasome, Apoptosis, DNA Damage/DNA Repair

  • CAS Number

    81198

  • Purity

    0.9918

  • Molecular Formula

    C15H12O3

  • Molecular Weight

    240.25

  • SMILES

    Oc1ccc(cc1)C1=Cc2ccc(O)cc2OC1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound