Phenylpyropene A - CAS 189564-20-3

Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM) .1 Phenylpyropene A inhibits diacylglycerol acyltransferase (DGAT) in rat liver microsomes (IC50 = 78.7 μM) . It induces mortality in 100% of M. persicae when used at a concentration of 5 ppm.3

Others, Acyltransferase

Others, Metabolism

189541

C32H38O10

582.64

[H][C@@]12C[C@H](OC(C)=O)[C@@]3(C)Oc4cc(oc(=O)c4[C@H](O)[C@]3([H])[C@@]1(C)CC[C@H](OC(C)=O)[C@@]2(C)COC(C)=O)-c1ccccc1

-20°C

Ice Packs

Natural Product