Phillyrin - CAS 487-41-2

Phillyrin (Forsythin) is a novel AMPK activator, has anti-obesity effects in nutritive obesity mice, it can prevent lipid accumulation in HepG2 cells by blocking the expression of SREBP-1c and FAS through LKB1/AMPK activation. Phillyrin (Forsythin) may be a new preventive agent of acute lung injury in the clinical setting, it potentially contributes to the suppression of the activation of MAPK and NF-κB pathways, it also has protective effects on H2O2-induced oxidative stress and apoptosis in PC12 cells.

Cytochromes P450, Influenza Virus, AMPK, Antibacterial

PI3K/Akt/mTOR signaling, Metabolism, Chromatin/Epigenetic, Microbiology/Virology

444

0.9971

C27H34O11

534.55

COc1ccc(cc1OC)[C@@H]1OC[C@H]2[C@@H]1CO[C@@H]2c1ccc(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1OC

-20°C

Ice Packs

Natural Product