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Phleomycin E - CAS 11031-13-3
Phleomycin E - CAS 11031-13-3
SKU:MF-0123812-01
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Product Details
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Bioactivity
Phleomycin E is a peptide-based antibiotic that is effective against Gram-positive and Gram-negative bacteria as well as mycobacteria. It extends the survival time of mice with transplanted Ehrlich ascites carcinoma and shows inhibitory effects on murine pulmonary solid tumors, with an IC50 of 0.31 μg/mL.
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Target
Antibacterial, Antibiotic
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Related Pathways
Microbiology/Virology
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CAS Number
11031-13-3
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Molecular Formula
C60H97N23O21S2
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Molecular Weight
1540.68
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SMILES
O=C(OC1C(O)C(OC(CO)C1O)OC2C(OC(C3=CN=CN3)C(NC(=O)C4=NC(=NC(N)=C4C)C(NCC(N)C(=O)N)CC(=O)N)C(=O)NC(C)C(O)C(C(=O)NC(C(=O)NCCC5=NC(C6=NC(=CS6)C(=O)NCCCCNC(=N)NCCCCNC(=N)N)CS5)C(O)C)C)OC(CO)C(O)C2O)N
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Natural Product