Phloretin - CAS 60-82-2

Phloretin (NSC-407292) is a well-known inhibitor of eukaryotic urea transporters, blocks VacA-mediated urea and ion transport. Phloretin is a dihydrochalcone, a type of natural phenols. It can be found in apple tree leaves and the Manchurian apricot. It promotes potent antioxidative activities in peroxynitrite scavenging and the inhibition of lipid peroxidation. It has been found to inhibit the growth of several cancer cells and induce apoptosis of B16 melanoma and HL60 human leukemia cells.

Endogenous Metabolite, SGLT, Urea Transporter, transporter

Membrane transporter/Ion channel, GPCR/G Protein, Metabolism

-24

>99.99%

C15H14O5

274.27

C(CCC1=CC=C(O)C=C1)(=O)C2=C(O)C=C(O)C=C2O

-20°C

Ice Packs

Natural Product