Phorbol 12-myristate 13-acetate - CAS 16561-29-8

Phorbol 12-myristate 13-acetate (PMA) is a natural phorbol ester that acts as an activator of PKC, SphK, and NF-κB, and is commonly used to induce differentiation of THP-1 cells and establish dermatitis models.

PKC, S1P Receptor, NF-κB

Chromatin/Epigenetic, GPCR/G Protein, NF-κB, Cytoskeletal Signaling

16524

>99.99%

C36H56O8

616.83

[H][C@]12[C@]3([H])C=C(CO)C[C@]4(O)C(=O)C(C)=C[C@@]4([H])[C@@]3(O)[C@H](C)[C@@H](OC(=O)CCCCCCCCCCCCC)[C@@]1(OC(C)=O)C2(C)C

-20°C

Ice Packs

Natural Product