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Phthalimidinoglutarimide-piperidine-NH-Boc - CAS 2229720-55-0
Phthalimidinoglutarimide-piperidine-NH-Boc - CAS 2229720-55-0
SKU:MF-0121139-01
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Product Details
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Bioactivity
Phthalimidinoglutarimide-piperidine-NH-Boc, a conjugate of E3 ligase ligand and linker, consists of Thalidomide and the corresponding Linker. It serves as a Cereblon ligand to recruit CRBN protein and acts as a key intermediate for synthesizing complete PROTAC molecules.
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Target
E3 Ligase Ligand-Linker Conjugate
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Related Pathways
PROTAC
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CAS Number
2229720-55-0
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Molecular Formula
C23H30N4O5
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Molecular Weight
442.51
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SMILES
O=C1N(CC=2C1=CC=C(C2)N3CCC(NC(OC(C)(C)C)=O)CC3)C4C(=O)NC(=O)CC4
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
PROTAC