PI-103 Hydrochloride - CAS 371935-79-4

PI-103 Hydrochloride is a dual PI3K/Akt and mTOR inhibitor exhibiting nM-level inhibition of p110α, p110β, p110δ, p110γ, DNA-PK, mTORC1, and mTORC2. PI-103 induces autophagy, mitochondrial apoptosis, and cell cycle arrest, making it suitable for leukaemia research.

Akt, Cell Cycle Arrest, Apoptosis, DNA-PK, Autophagy, mTOR, PI3K, Mitochondrial Metabolism

PI3K/Akt/mTOR signaling, Cell Cycle/Checkpoint, Autophagy, Cytoskeletal Signaling, Apoptosis, Metabolism, DNA Damage/DNA Repair

371935-79-4

0.9707

C19H17ClN4O3

384.82

Cl.Oc1cccc(c1)-c1nc(N2CCOCC2)c2oc3ncccc3c2n1

-20°C

Ice Packs

Small Compound