PI-1840 - CAS 1401223-22-0

PI-1840 (IC50 = 27 nM) is a reversible and selective chymotrypsin-like (CT-L) inhibitor, with little proteasome proteolytic effects on trypsin-like (T-L) and postglutamyl-peptide-hydrolysis-like (PGPH-L) .

Autophagy, Apoptosis, PARP, Caspase, NF-κB, Bcl-2 Family, Proteasome

NF-κB, Proteases/Proteasome, Autophagy, DNA Damage/DNA Repair, Apoptosis, Ubiquitination, Chromatin/Epigenetic

1401201

>99.99%

C22H26N4O3

394.47

CCCc1ccc(OCC(=O)N(Cc2nc(no2)-c2cccnc2)C(C)C)cc1

-20°C

Ice Packs

Small Compound