PI3K/Akt/mTOR-IN-3 - CAS 2457245-94-0

PI3K/Akt/mTOR-IN-3 is a potent inhibitor of PI3K/Akt/mTOR. PI3K/Akt/mTOR-IN-3 inhibits the migration of MCF-7 cells (IC50: 0.77 μM), HeLa cells (IC50: 1.23 μM) and HepG2 cells (IC50: 4.57 μM) . PI3K/Akt/mTOR-IN-3 inhibited the migration of MCF-7 and HeLa cells at a concentration of 4 μM. PI3K/Akt/mTOR-IN-3 blocked the cell cycle in S phase and induced apoptosis.

MTOR, Apoptosis, Akt, Others, PI3K

Cytoskeletal Signaling, PI3K/Akt/mTOR signaling, Apoptosis, Others

2457151

C34H51NO2

505.77

C(NCC=C)(=O)[C@]12[C@](C=3[C@@](C)(CC1)[C@@]4(C)[C@](CC3)([C@]5(C)[C@@](CC4)(C(C)(C)C(=O)C(=C)C5)[H])[H])(CC(C)(C)CC2)[H]

-20°C

Ice Packs

Small Compound