Molfinity

PI3Kδ/BET-IN-1 - CAS 3054869-10-9

SKU:MF-0112822-01

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Product Details

Bioactivity
PI3Kδ/BET-IN-1 (compound 10b) exhibits excellent and balanced activity against PI3Kδ (IC50= 112 nM) and BRD4-BD1 (IC50= 19 nM), while also demonstrating strong antiproliferative effects in DLBCL cells.
Target
Epigenetic Reader Domain, PI3K
Related Pathways
PI3K/Akt/mTOR signaling, Chromatin/Epigenetic
CAS Number
3054850
Molecular Formula
C27H34N6O3S
Molecular Weight
522.662
SMILES
O=C1C=2NC=CC2C(=CN1C)C3=NC=4C=C(SC4C(=N3)N5CCOCC5)CN6CCC(CC6)C(O)(C)C
Storage Temperature
-20°C
Shipping Conditions
Ice Packs
Category
Small Compound