PI3K/HDAC-IN-2 - CAS 2361418-65-5

PI3K/HDAC-IN-2 is a potent dual PI3K/HDAC inhibitor with IC50 values of 226 nM for PI3Kα, 279 nM for PI3Kβ, 467 nM for PI3Kγ, 29 nM for PI3Kδ, and 1.3 nM for HDAC1. PI3K/HDAC-IN-2 is selective for PI3Kδ and class I and IIb HDACs, exhibiting significant anticancer effects.

Others, PI3K, HDAC

Others, PI3K/Akt/mTOR signaling, DNA Damage/DNA Repair, Chromatin/Epigenetic

2361348

C23H23N7O4

461.47

O(CCN(C)C=1N=CC(C(NO)=O)=CN1)C=2C3=C(C=C(C2)C=4C=CC(OC)=NC4)C(C)=NC=N3

-20°C

Ice Packs

Small Compound