PI3Kδ-IN-10 - CAS 2409725-49-9

PI3Kδ-IN-10 is a highly potent and orally active PI3Kδ inhibitor (IC50 = 2 nM) that robustly suppresses the downstream AKT pathway to induce subsequent apoptosis in hepatocellular carcinoma models.

Others, PI3K, Apoptosis, Akt

PI3K/Akt/mTOR signaling, Others, Cytoskeletal Signaling, Apoptosis

2409725-49-9

C19H16ClN9

405.84

[C@H](NC=1C(C#N)=C(N)N=C(N)N1)(C)C=2C=3C(N(N2)C=4C=CC=NC4)=CC(Cl)=CC3

-20°C

Ice Packs

Small Compound