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PI3Kα-IN-16 - CAS 1448711-61-2

PI3Kα-IN-16 - CAS 1448711-61-2

MF-0147727-01

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Product Details

  • Bioactivity

    PI3Kα-IN-16 (Z86) is a recently developed inhibitor of PI3Kα, displaying an IC 50 of 4.28 μM. With potent efficacy, it inhibits the growth and migration of CRCs mediated by PI3K. Additionally, PI3Kα-IN-16 also suppresses the Wnt signaling pathway [1].

  • Target

    PI3K, Wnt/beta-catenin

  • Related Pathways

    PI3K/Akt/mTOR signaling, Stem Cells, Cytoskeletal Signaling

  • CAS Number

    1448711-61-2

  • Molecular Formula

    C27H24N2O2

  • Molecular Weight

    408.49

  • SMILES

    C(C)N1C=2C(C=3C1=CC=CC3)=CC(C(OC(C)C)=O)=NC2C=4C5=C(C=CC4)C=CC=C5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound