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PI3Kδ-IN-23 - CAS 3051828-81-7
PI3Kδ-IN-23 - CAS 3051828-81-7
SKU:MF-0112710-01
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Product Details
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Bioactivity
PI3Kδ-IN-23 (compound A11) is a potent inhibitor of PI3Kδ, with an IC50 of 0.27 nM. It binds to PI3Kδ through covalent interaction with Lys779 and plays a significant role in cancer research.
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Target
PI3K
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Related Pathways
PI3K/Akt/mTOR signaling
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CAS Number
3051740
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Molecular Formula
C30H30N6O5
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Molecular Weight
554.596
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SMILES
N(C=1C2=C(C=CC(=N2)C=3C=C(C(OC4=CC=CC=C4)=O)C(OC)=NC3)N=CN1)[C@@H]5CN(C(=O)C6CCOCC6)CC5
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound