PI3Kδ-IN-24 - CAS 3051829-20-7

PI3Kδ-IN-24 is a selective inhibitor of PI3Kδ with an IC50 value of 0.1 nM. It exhibits significant antiproliferative effects on cancer cell lines that overexpress PI3Kδ. PI3Kδ-IN-24 reduces p-AKT levels and induces cell cycle arrest and apoptosis in tumor cells. This compound is applicable for cancer research, particularly in diffuse large B-cell lymphoma (DLBCL) .

PI3K, Akt, Apoptosis

PI3K/Akt/mTOR signaling, Apoptosis, Cytoskeletal Signaling

3051802

C28H29N7O4

527.57

N([C@H](C(=O)N1CCN(C)CC1)C)C=2C3=C(C=CC(=N3)C=4C=C(C(OC5=CC=CC=C5)=O)C(OC)=NC4)N=CN2

-20°C

Ice Packs

Small Compound