PI3K-IN-29 - CAS 2768005-77-0

PI3K-IN-29, a potent inhibitor of PI3K, exhibits substantial inhibition capabilities against U87MG, HeLa, and HL60 cells, with IC50 values of 0.264, 2.04, and 1.14 μM, respectively. It effectively blocks the PI3K/Akt signaling pathway by preventing the PI3K-catalyzed phosphorylation of Akt [1].

Others, Akt, PI3K

Cytoskeletal Signaling, Others, PI3K/Akt/mTOR signaling

2767928

C27H22ClN7O3S

560.03

N(S(=O)(=O)C1=CC=CC=C1)C2=CC(C3=CC=4C(=CN=NC4C=C3)C=5C=NC(=NC5)N6CCOCC6)=CN=C2Cl

-20°C

Ice Packs

Small Compound