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PI3Kδ/γ-IN-3 - CAS 2730151-31-0

PI3Kδ/γ-IN-3 - CAS 2730151-31-0

SKU:MF-0138470-01

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  • Bioactivity

    PI3Kδ/γ-IN-3 (Compound 58) is an orally active dual inhibitor of PI3Kδ (IC50: 1 nM) and PI3Kγ (IC50: 16 nM), effective in inducing apoptosis of tumor cells and applicable to B-cell malignant tumor studies.

  • Target

    Others, PI3K, Apoptosis

  • Related Pathways

    PI3K/Akt/mTOR signaling, Apoptosis, Others

  • CAS Number

    2730120

  • Molecular Formula

    C23H20ClN9O

  • Molecular Weight

    473.92

  • SMILES

    O=C1N(C(=NC=2C1=C(Cl)C=CC2)[C@H]3N([C@@H](C)CC3)C=4C(C#N)=C(N)N=C(N)N4)C=5C=CC=NC5

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound