PI3K-IN-35 - CAS 2458163-99-8

PI3K-IN-35 (Compound 6l) is a highly selective inhibitor of PI3K, targeting PI3K-α (IC50: 13.98 μM), PI3K-β (IC50: 7.22 μM), and PI3K-δ (IC50: 10.94 μM) . It blocks the cell cycle in the G2/M phase and induces apoptosis, making it useful for studying leukemia.

Others, PI3K, Apoptosis

Apoptosis, PI3K/Akt/mTOR signaling, Others

2458056

C25H23N7O2

453.5

C(#N)C=1C(=NC(NN=CC=2C=3C(NC2)=CC=CC3)=NC1N4CCOCC4)C5=CC=C(OC)C=C5

-20°C

Ice Packs

Small Compound