PI3K/mTOR Inhibitor-12 - CAS 2891692-83-2

PI3K/mTOR Inhibitor-12, a potent and selective orally active inhibitor, exhibits IC50 values of 0.06 nM for PI3Kα and 3.12 nM for mTOR, indicating significant antitumor activity with reduced liver toxicity [1].

MTOR, PI3K

PI3K/Akt/mTOR signaling

2891607

C27H27F2N9O4S

611.62

COC1=C(C=C(C=N1)C2=NN3C(=NC=C3C4=CN(N=N4)CCCN5CCOCC5)C=C2)NS(=O)(=O)C6=C(C=C(C=C6)F)F

-20°C

Ice Packs

Small Compound