PI4KIII beta inhibitor 5 - CAS 3029506-23-5

PI4KIII beta inhibitor 5 (Compound 43) is an inhibitor of PI4KIIIβ with an IC50 of 19 nM. By inhibiting the PI3K/AKT pathway, it induces apoptosis in cancer cells, causes cell cycle arrest at the G2/M phase, and promotes autophagy. Additionally, PI4KIII beta inhibitor 5 demonstrates significant anti-tumor activity in the H446 small cell lung cancer xenograft model. This compound is applicable in cancer research studies.

PI4K

PI3K/Akt/mTOR signaling

3029478

C24H27F2N3O4S2

523.616

O=C(NC1=NC(=C(S1)C=2C=CC(OC)=C(C2)S(=O)(=O)NCC3=CC=C(F)C=C3F)C)CCCCC

-20°C

Ice Packs

Small Compound