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Molfinity

Pico145 - CAS 1628287-16-0

Pico145 - CAS 1628287-16-0

MF-0019988-01

$60.08 USD
$60.08 USD
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Product Details

  • Bioactivity

    Pico145 (HC-608) is a remarkable inhibitor of TRPC1/4/5 channels, specifically inhibiting () -englerin A-activated TRPC4/TRPC5 channels with IC50s of 0.349 and 1.3 nM in cells, while showing no effect on TRPC3, TRPC6, TRPV1, TRPV4, TRPA1, TRPM2, or TRPM8.

  • Target

    TRP/TRPV Channel

  • Related Pathways

    Membrane transporter/Ion channel

  • CAS Number

    1628271

  • Purity

    0.9906

  • Molecular Formula

    C23H20ClF3N4O5

  • Molecular Weight

    524.88

  • SMILES

    Cn1c2nc(Oc3cccc(OC(F)(F)F)c3)n(Cc3ccc(Cl)cc3)c2c(=O)n(CCCO)c1=O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound