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Molfinity

Picropodophyllin - CAS 477-47-4

Picropodophyllin - CAS 477-47-4

MF-0014556-01

$53.35 USD
$53.35 USD
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Product Details

  • Bioactivity

    Picropodophyllin (Picropodophyllin (PPP) ) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM) . Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with activities of other growth factor receptors, such as receptors for insulin, epidermal growth factor, platelet-derived growth factor, fibroblast growth factor and mast/stem cell growth factor (KIT) .

  • Target

    Apoptosis, IGF-1R

  • Related Pathways

    Tyrosine Kinase/Adaptors, Apoptosis

  • CAS Number

    426

  • Purity

    0.9983

  • Molecular Formula

    C22H22O8

  • Molecular Weight

    414.41

  • SMILES

    [H][C@]12COC(=O)[C@@]1([H])[C@H](c1cc(OC)c(OC)c(OC)c1)c1cc3OCOc3cc1[C@@H]2O

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product