Pimaric acid - CAS 127-27-5

Pimaric acid is a naturally occurring resin acid identified in species such as Aralia cordata and various pine trees. Pimaric acid exerts anticancer effects through induction of endoplasmic reticulum stress, activation of caspase-dependent apoptosis, cell cycle arrest, and inhibition of cell migration in ovarian cancer cells. Additionally, pimaric acid suppresses mRNA expression, protein levels, and promoter activity of matrix metalloproteinase-9 (MMP-9) in TNF-α-stimulated human aortic smooth muscle cells (HASMCs), supporting its role in cancer and vascular research.

MMP, p38 MAPK, NF-κB, Apoptosis

Proteases/Proteasome, NF-κB, Apoptosis, MAPK

95

0.8

C20H30O2

302.45

[H][C@]12CC[C@@](C)(C=C)C=C1CC[C@@]1([H])[C@@](C)(CCC[C@]21C)C(O)=O

-20°C

Ice Packs

Natural Product