Pinokalant - CAS 149759-26-2

Pinokalant (LOE-908) is a novel non-selective cation channel inhibitor.Pinokalant significantly reduces cortical infarct volume in in vivo experiments, improves the metabolic and electrophysiological status of the ischemic penumbra region, and reduces the size of the lesion on magnetic resonance images in the acute phase after middle cerebral artery occlusion in rats.Pinokalant is a potential SARS-CoV-2 protease inhibitor for the study of stroke.

SARS-CoV, TRP/TRPV Channel

Microbiology/Virology, Membrane transporter/Ion channel

149731

0.9909

C41H48N2O9

712.83

C(C(N(CCC1=C(OC)C(OC)=C(OC)C=C1)CCC2=C(OC)C(OC)=C(OC)C=C2)=O)(C=3C=4C(=CC(OC)=C(OC)C4)CCN3)C5=CC=CC=C5

-20°C

Ice Packs

Small Compound