Pinoresinol - CAS 487-36-5

Pinoresinol ((+) -Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative stress preserving pial blood flow distribution; it may exert pharmacologically interesting effects via modulation of the insulin-like signalling pathway in C.elegans. Pinoresinol causes an upregulation of the CDK inhibitor p21 (WAF1/Cip1) both at mRNA and protein levels, inhibits NF-kappaB and activating protein 1 (AP-1) .

CDK, p53, Apoptosis, NF-κB

Apoptosis, NF-κB, Cell Cycle/Checkpoint

446

0.9867

C20H22O6

358.39

[H][C@]12CO[C@H](c3ccc(O)c(OC)c3)[C@@]1([H])CO[C@@H]2c1ccc(O)c(OC)c1

-20°C

Ice Packs

Natural Product