Pirarubicin HCl - CAS 95343-20-7

Pirarubicin HCl is the hydrochloride salt form of pirarubicin, an analogue of the anthracycline antineoplastic antibiotic doxorubicin with antineoplastic activity. Pirarubicin intercalates into DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair as well as RNA and protein synthesis. This agent is less cardiotoxic than doxorubicin and exhibits activity against some doxorubicin-resistant cell lines.

Antibacterial, Topoisomerase, Antibiotic, Autophagy, Others

DNA Damage/DNA Repair, Others, Autophagy, Microbiology/Virology

95316

C32H38ClNO12

664.1

Cl.[H][C@]1(CCCCO1)O[C@H]1[C@@H](N)C[C@]([H])(O[C@H]2C[C@@](O)(Cc3c(O)c4C(=O)c5cccc(OC)c5C(=O)c4c(O)c23)C(=O)CO)O[C@H]1C

-20°C

Ice Packs

Small Compound