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PK7242 - CAS 1446352-68-6
PK7242 - CAS 1446352-68-6
SKU:MF-0117941-01
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Product Details
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Bioactivity
PK7242 is an inducer that reactivates mutant p53 in cancer cells. In cancer cells harboring the Y220C mutation, PK7242 binds to the core domain of p53-Y220C, leading to the inhibition of cell growth, cell cycle arrest, and apoptosis.
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Target
MDM-2/p53
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Related Pathways
Apoptosis
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CAS Number
1446278
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Molecular Formula
C17H19FN4
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Molecular Weight
298.36
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SMILES
FC=1C=CC(=CC1)C2=CN(N=C2N3C=CC=C3)CCN(C)C
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound