PKC β pseudosubstrate - CAS 172308-76-8

Selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM) . Consists of amino acids 19 - 31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide.

PKC

Chromatin/Epigenetic, Cytoskeletal Signaling

172224

C177H294N62O38S3

3994.84

-20°C

Ice Packs

Peptide