PKCTheta-IN-2 - CAS 1810742-60-9

PKCTheta-IN-2 (compound 14) is a potent and selective PKCθ inhibitor (IC50 = 0.25 nM) that suppresses IL-2 production in mice (IC50 = 682 nM) .

PKC

Cytoskeletal Signaling, Chromatin/Epigenetic

1810673

0.9938

C24H23N5O2

413.47

[C@H](C)(N1C=2C(C(=O)NC1(C)C)=CC=C(C2)N3C=4C(NC3=O)=NC=CC4)C5=CC=CC=C5

-20°C

Ice Packs

Small Compound