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PKF050-638 - CAS 528893-52-9
PKF050-638 - CAS 528893-52-9
SKU:MF-0033794-01
Regular price
$1,383.80 USD
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$1,383.80 USD
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Product Details
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Bioactivity
PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction. PKF050-638 is an effective and selective inhibitor of HIV-1 Rev (IC50=0.04 μM) .
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Target
HIV Protease, CRM1
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Related Pathways
Proteases/Proteasome, Microbiology/Virology, Membrane transporter/Ion channel
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CAS Number
528832
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Molecular Formula
C13H13ClN4O2
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Molecular Weight
292.72
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SMILES
C(=C\C(OCC)=O)\N1C(=NC=N1)C2=C(N)C=CC(Cl)=C2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound