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PKF050-638 - CAS 528893-52-9

PKF050-638 - CAS 528893-52-9

SKU:MF-0033794-01

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  • Bioactivity

    PKF050-638 inhibits the CRM1-mediated Rev nuclear export by disrupting CRM1-NES interaction. PKF050-638 is an effective and selective inhibitor of HIV-1 Rev (IC50=0.04 μM) .

  • Target

    HIV Protease, CRM1

  • Related Pathways

    Proteases/Proteasome, Microbiology/Virology, Membrane transporter/Ion channel

  • CAS Number

    528832

  • Molecular Formula

    C13H13ClN4O2

  • Molecular Weight

    292.72

  • SMILES

    C(=C\C(OCC)=O)\N1C(=NC=N1)C2=C(N)C=CC(Cl)=C2

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound