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PKI-166 - CAS 187724-61-4
PKI-166 - CAS 187724-61-4
SKU:MF-0033795-01
Regular price
$36.16 USD
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$36.16 USD
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Product Details
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Bioactivity
PKI-166 is an oral inhibitor of EGF-R tyrosine kinase (IC50:0.7 nM) that is both effective and selective. PKI-166 can effectively inhibit the growth and metastasis of various human cancer cells including pancreatic cancer.
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Target
EGFR, VEGFR
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Related Pathways
Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors
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CAS Number
187659
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Purity
0.998
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Molecular Formula
C20H18N4O
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Molecular Weight
330.38
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SMILES
C[C@@H](Nc1ncnc2[nH]c(cc12)-c1ccc(O)cc1)c1ccccc1
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound