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Molfinity

PKI-166 - CAS 187724-61-4

PKI-166 - CAS 187724-61-4

SKU:MF-0033795-01

Regular price $36.16 USD
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  • Bioactivity

    PKI-166 is an oral inhibitor of EGF-R tyrosine kinase (IC50:0.7 nM) that is both effective and selective. PKI-166 can effectively inhibit the growth and metastasis of various human cancer cells including pancreatic cancer.

  • Target

    EGFR, VEGFR

  • Related Pathways

    Angiogenesis, JAK/STAT signaling, Tyrosine Kinase/Adaptors

  • CAS Number

    187659

  • Purity

    0.998

  • Molecular Formula

    C20H18N4O

  • Molecular Weight

    330.38

  • SMILES

    C[C@@H](Nc1ncnc2[nH]c(cc12)-c1ccc(O)cc1)c1ccccc1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound