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PKI (5-22) amide - CAS 100853-58-5
PKI (5-22) amide - CAS 100853-58-5
SKU:MF-0156007-01
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Product Details
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Bioactivity
PKI (5-22) amide, an active inhibitory fragment of the cyclic AMP-dependent protein kinase (PKA) inhibitor, effectively prevents PKA activation. However, it does not reduce the homologous desensitization of CRF1 receptors [1] [2].
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Target
PKA
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Related Pathways
Tyrosine Kinase/Adaptors
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CAS Number
100790
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Molecular Formula
C84H137N29O26
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Molecular Weight
1969.17
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SMILES
CC[C@H](C)[C@H](NC(=O)[C@H](C)NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CCCNC(N)=N)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](C)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](C)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](NC(=O)[C@@H](N)[C@@H](C)O)[C@@H](C)O)[C@@H](C)CC)[C@@H](C)O)C(N)=O
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Peptide