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Molfinity

PKM2-IN-6 - CAS 771467-00-6

PKM2-IN-6 - CAS 771467-00-6

MF-0100494-01

$96.50 USD
$96.50 USD
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Product Details

  • Bioactivity

    PKM2-IN-6 (compound 7d) is an orally active PKM2 inhibitor (IC50=23 nM) capable of inducing apoptosis and G2 cell cycle arrest. It reduces PKM1 and PKM2 expression at the mRNA level, exhibits antitumour activity, and is suitable for investigating triple-negative breast cancer (TNBC) .

  • Target

    PKM, Apoptosis

  • Related Pathways

    Apoptosis, Metabolism

  • CAS Number

    771467-00-6

  • Purity

    0.9983

  • Molecular Formula

    C17H14N4OS

  • Molecular Weight

    322.38

  • SMILES

    N(C1=NC(C=2N3C(=NC2)C=CC=C3)=CS1)C4=C(OC)C=CC=C4

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound