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PKMYT1-IN-7 - CAS 2986404-30-0

PKMYT1-IN-7 - CAS 2986404-30-0

MF-0114767-01

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Product Details

  • Bioactivity

    PKMYT1-IN-7 (compound 7) is an orally active PKMYT1 inhibitor with IC50 values of 1.6 nM for PKMYT1 and 0.06 μM for pCDK1. It inhibits the phosphorylation of CDK1 at T14 and Y15 sites and exhibits anticancer activity both in vitro and in vivo.

  • Target

    CDK, Wee1

  • Related Pathways

    Cell Cycle/Checkpoint

  • CAS Number

    2986374

  • Molecular Formula

    C17H18FN5O3

  • Molecular Weight

    359.355

  • SMILES

    O=C(N)C=1C=2C(=O)N(C(=NC2N(C1N)C=3C(=CC=C(O)C3C)C)C)CF

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound