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PKR-IN-C16 - CAS 608512-97-6

PKR-IN-C16 - CAS 608512-97-6

MF-0012072-01

$36.91 USD
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Product Details

  • Bioactivity

    PKR-IN-C16 is a specific protein kinase (PKR) inhibitor. PKR-IN-C16 is able to inhibit the autophosphorylation of PKR and unlock the translation blockade induced by PKR in primary neuronal cultures.PKR-IN-C16 binds the ATP-binding site of PKR and blocks autophosphorylation with an IC50 value of 186-210 nM. PKR-IN-C16 protects human neuroblastoma cells against cell damage triggered by tunicamycin-mediated endoplasmic reticulum stress.

  • Target

    Apoptosis, Others

  • Related Pathways

    Others, Apoptosis

  • CAS Number

    608512-97-6

  • Purity

    0.9948

  • Molecular Formula

    C13H8N4OS

  • Molecular Weight

    268.29

  • SMILES

    O=C1Nc2ccc3ncsc3c2\C1=C\c1cnc[nH]1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound