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Molfinity

PKR-IN-C51 - CAS 1314594-23-4

PKR-IN-C51 - CAS 1314594-23-4

MF-0094446-01

$89.19 USD
$89.19 USD
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Product Details

  • Bioactivity

    PKR-IN-C51 is a dose-dependent and ATP-competitive protein kinase R (PKR) inhibitor that inhibits intracellular PKR activation and autophosphorylation in mouse macrophages with an IC50=9 μM and Ki=3.4 μM.Interferon-induced double-stranded RNA-activated protein kinase (PKR) is a widely expressed Ser/Thr kinase.

  • Target

    Serine Protease, Serine/threonin kinase

  • Related Pathways

    Cell Cycle/Checkpoint, Proteases/Proteasome, Metabolism

  • CAS Number

    1314567

  • Purity

    0.9894

  • Molecular Formula

    C23H21N5

  • Molecular Weight

    367.45

  • SMILES

    N1=CC=C(N=C1NCCC2=CNC=3C=CC=CC32)C=4C=5C=CC=CC5NC4C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound