Platycodin D - CAS 58479-68-8

Platycodin D may stimulate TNF-α synthesis or inhibit degradation of TNF-α mRNA. Platycodin D (10/30 μM) suppresses prostaglandin E2 production in rat peritoneal macrophages stimulated by the protein kinase C activator 12-O-tetradecanoyl phorbol 13-acetate (TPA) . Platycodin D and D3 are useful as expectorant agents in the treatment of various airway diseases, they can increase mucin release from rat and hamster tracheal surface epithelial cell culture and also from intact rat trachea upon nebulization.

AMPK, Prostaglandin Receptor, Wnt/beta-catenin

Stem Cells, Cytoskeletal Signaling, GPCR/G Protein, Chromatin/Epigenetic, Immunology/Inflammation, PI3K/Akt/mTOR signaling

58403

0.9979

C57H92O28

1225.32

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-20°C

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Natural Product