Plevitrexed - CAS 153537-73-6

Plevitrexed is taken up via the α-folate receptor as well as the reduced folate carrier. Plevitrexed is an orally active and effective thymidylate synthase (TS) inhibitor (Ki: 0.44 nM) . Plevitrexed is used for gastric cancer in clinical.

Others, DNA/RNA Synthesis

DNA Damage/DNA Repair, Cell Cycle/Checkpoint, Others

153458

C26H25FN8O4

532.53

O=C1C=2C(=CC(C)=C(CN(CC#C)C3=CC(F)=C(C(N[C@@H](CCC=4NN=NN4)C(O)=O)=O)C=C3)C2)NC(C)=N1

-20°C

Ice Packs

Small Compound