PLK1/BRD4-IN-2 - CAS 2251709-89-2

PLK1/BRD4-IN-2 (compound 15), an analog of BI-2536, simultaneously inhibits both Polo-like kinase 1 (PLK1 IC 50 = 40 nM) and BRD4 bromodomain (BRD4-BD1 IC 50 = 28 nM) as a dual inhibitor [1].

Epigenetic Reader Domain

Chromatin/Epigenetic

2251709-89-2

C27H36N6O3

492.61

C[C@H]1N(C=2C(N(C)C1=O)=CN=C(NC3=C(OC)C=C(C(=O)N4CCCCCC4)C=C3)N2)C5CCCC5

-20°C

Ice Packs

Small Compound