PLK1-IN-15 - CAS 3068529-37-0

PLK1-IN-15 is a PLK1 inhibitor with an IC50 of 38.5 nM. It exhibits antiproliferative effects on HepG2, Huh7, H1299, and A549 cells, with IC50 values of 2.03, 2.08, 4.79, and 17.11 μM, respectively. Additionally, PLK1-IN-15 can induce cell cycle arrest in the G2/M phase and trigger apoptosis (Apoptosis), demonstrating anticancer activity.

Apoptosis, PLK

Cell Cycle/Checkpoint, Apoptosis

3068492

C25H29N7O4S

523.61

O=C(OC)C1=C(SC2=C1CCCC2)NC3=NC(=NC=C3N(=O)=O)NC4=CC=C(C=C4)N5CCN(C)CC5

-20°C

Ice Packs

Small Compound