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Molfinity

PLX5622 - CAS 1303420-67-8

PLX5622 - CAS 1303420-67-8

MF-0094988-01

$38.41 USD
$38.41 USD
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Product Details

  • Bioactivity

    PLX5622 is an orally active small-molecule CSF1R inhibitor that selectively depletes microglia in the brains of mice and rats. It is commonly used to establish models related to microglia-associated neuroinflammation, neurodegenerative diseases (such as Alzheimer's disease and Parkinson's disease), brain injury, and neuroimmune regulation.

  • Target

    CSF-1R, c-Fms

  • Related Pathways

    Tyrosine Kinase/Adaptors

  • CAS Number

    1303345

  • Purity

    0.9992

  • Molecular Formula

    C21H19F2N5O

  • Molecular Weight

    395.41

  • SMILES

    COc1ncc(F)cc1CNc1ccc(Cc2c[nH]c3ncc(C)cc23)c(F)n1

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound