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Molfinity

PLX7904 - CAS 1393465-84-3

PLX7904 - CAS 1393465-84-3

MF-0019962-01

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Product Details

  • Bioactivity

    PLX7904 (PB04), also known as PB04, is a potent and selective paradox-breaker RAF inhibitor. It is able to efficiently inhibit activation of ERK1/2 in mutant BRAF melanoma cells but does not hyperactivate ERK1/2 in mutant RAS-expressing cells.

  • Target

    Raf

  • Related Pathways

    MAPK

  • CAS Number

    1393378

  • Purity

    0.9966

  • Molecular Formula

    C24H22F2N6O3S

  • Molecular Weight

    512.53

  • SMILES

    CCN(C)S(=O)(=O)Nc1ccc(F)c(C(=O)c2c[nH]c3ncc(cc23)-c2cnc(nc2)C2CC2)c1F

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound