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Molfinity

PM050489 - CAS 960210-97-3

PM050489 - CAS 960210-97-3

MF-0155335-01

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Product Details

  • Bioactivity

    PM050489, a potent polyketone inhibitor of Microtubule/Tubulin isolated from the Madagascan sponge Lithoplocamia lithistoides, effectively inhibits mitosis with an IC 50 value of 26.4 nM. This compound exhibits antitumor activity, making it relevant for cancer research [1] [2].

  • Target

    Others, Microtubule Associated

  • Related Pathways

    Others, Cytoskeletal Signaling

  • CAS Number

    960110

  • Molecular Formula

    C31H44ClN3O7

  • Molecular Weight

    606.15

  • SMILES

    [C@@H](/C=C(/C=C\C=C/C(N[C@H](C(N/C=C\C[C@H](C/C=C(\C)/Cl)OC(N)=O)=O)[C@@](C)(C)C)=O)\C)(C)[C@]1(OC(=O)C(OC)=CC1)[H]

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Natural Product