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PM534 - CAS 2446376-25-4
PM534 - CAS 2446376-25-4
SKU:MF-0121186-01
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Product Details
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Bioactivity
PM534, a tubulin-targeting agent, inhibits tubulin assembly with IC50 values of 0.8-3.2 nM. PM534 binds to the colchicine site of tubulin, demonstrating high antitumor activity [1].
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Target
Microtubule Associated
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Related Pathways
Cytoskeletal Signaling
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CAS Number
2446376-25-4
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Molecular Formula
C20H27N3O5S
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Molecular Weight
421.51
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SMILES
[C@@H](NC(=O)[C@@]1(C)N=C(\C(=N\O)\C)SC1)(CCC)C2=CC(OCC3CC3)=CC(=O)O2
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Storage Temperature
-20°C
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Shipping Conditions
Ice Packs
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Category
Small Compound