PMED-1 - CAS 491828-75-2

PMED-1, a β-catenin inhibitor, effectively suppresses β-catenin activity in hepatoblastoma cells and various HCC (Hepatocellular Carcinoma) cells with IC50 values ranging from 4.87 to 32 μM. It impedes cell proliferation by disrupting the interaction between β-catenin and CREB-binding protein, thus affecting Wnt signaling pathways. PMED-1 is utilized in cancer research studies.

Wnt/beta-catenin

Stem Cells, Cytoskeletal Signaling

491751

C20H18FN3O

335.38

O=C(NC=1C=NN(C1)CC2=CC=C(F)C=C2)C3CC3C=4C=CC=CC4

-20°C

Ice Packs

Small Compound