PMX-53 - CAS 219639-75-5

PMX-53 is a Mas-related gene 2 (MrgX2) agonist and C5aR (CD88) antagonist. PMX-53 reduces atherosclerotic lesions in a mouse model of atherosclerosis, inhibits lung metastasis in a mouse breast cancer model, inhibits C5a-induced hypernociception in rats.

Complement System

Immunology/Inflammation

219559

C47H65N11O7

896.09

CC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H]1CCCNC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC(=O)[C@@H](CC2CCCCC2)NC(=O)[C@@H]2CCCN2C1=O

-20°C

Ice Packs

Peptide