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PNU-145156E - CAS 159537-58-3

PNU-145156E - CAS 159537-58-3

SKU:MF-0144803-01

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  • Bioactivity

    PNU-145156E (formerly FCE 26644) is a noncytotoxic small molecule that exerts antitumor activity through reversible complex formation with growth and angiogenic factors, thereby inhibiting their ability to induce angiogenesis. PNU-145156E is utilized in research on tumor vascularization, angiogenesis regulation, and the development of anti-angiogenic therapeutic strategies.

  • Target

    VEGFR, FGFR

  • Related Pathways

    Tyrosine Kinase/Adaptors, Angiogenesis

  • CAS Number

    159476

  • Molecular Formula

    C45H40N10O17S4

  • Molecular Weight

    1121.12

  • SMILES

    O=C(NC=1C=C(C(=O)NC=2C=C(C(=O)NC3=CC=C4C=C(C=C(C4=C3)S(=O)(=O)O)S(=O)(=O)O)N(C2)C)N(C1)C)NC=5C=C(C(=O)NC=6C=C(C(=O)NC7=CC=C8C=C(C=C(C8=C7)S(=O)(=O)O)S(=O)(=O)O)N(C6)C)N(C5)C

  • Storage Temperature

    -20°C

  • Shipping Conditions

    Ice Packs

  • Category

    Small Compound